Rat Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) Protein

Este producto es parte de CD163 - CD163 molecule
Rat Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163) Protein

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935106861

info@markelab.com

Precio

247€ (10 µg)

Protein CD163

proveedor

Abbexa

reference

abx167778

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat Cluster Of Differentiation 163 (CD163) Protein is a recombinant Rat protein expressed in E. coli.


Background

CD163, also known as the hemoglobin scavenger receptor, is a transmembrane glycoprotein expressed primarily on the surface of monocytes and macrophages. Encoded by the CD163 gene on chromosome 12 in humans, CD163 functions as a receptor for the haptoglobin-hemoglobin (Hp-Hb) complex. It is critical in scavenging free hemoglobin (Hb) released during red blood cell breakdown, thus protecting tissues from oxidative damage and inflammation due to free hemoglobin. Additionally, CD163 is part of the cysteine-rich scavenger receptor family and plays an important role in immune modulation, inflammation resolution, and tissue remodeling. Through its function as an anti-inflammatory receptor, CD163 contributes to the regulation of immune responses, often acting as a “sensor” for inflammatory conditions. When inflammation is detected, CD163-expressing cells can trigger responses that help protect tissues, making this molecule an essential component in maintaining immune homeostasis and limiting excessive immune reactions.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Scavenger Receptor Cysteine-Rich Type 1 Protein M130 (CD163)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 30.6 kDa Observed MW (SDS-PAGE): 36 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro693-Asp939 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD163


dry ice

No


availability

Shipped within 5-7 working days.


alias

Scavenger receptor cysteine-rich type 1 protein M130,M130,MM130,SCARI1,Hemoglobin scavenger receptor


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reactivity

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