Rat Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits PTPRC
proveedor
Abbexareference
abx257648Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Protein Tyrosine Phosphatase Receptor Type C / CD45 (PTPRC) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Protein Tyrosine Phosphatase Receptor Type C / CD45 (PTPRC) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTPRC, also known as CD45, is a receptor-type tyrosine phosphatase primarily expressed in hematopoietic cells. It regulates antigen receptor signaling in lymphocytes by dephosphorylating inhibitory residues on Src family kinases such as Lck and Fyn. Structurally, PTPRC has an extracellular domain, a single transmembrane region, and two cytoplasmic phosphatase domains, with the first being catalytically active. It is critical for T-cell and B-cell activation, development, and immune response regulation. Mutations in PTPRC are linked to severe immunodeficiency disorders, including SCID, and its overexpression is associated with autoimmune diseases and leukemia.
Características del producto
category
ELISA Kits
immunogen target
Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.08 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
LCA,LY5,B220,CD45,L-CA,T200,CD45R,GP180,IMD105,CD45,Leukocyte common antigen,Receptor-type tyrosine-protein phosphatase C
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTPRC
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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