Rat Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) Protein

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Rat Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) Protein is a Recombinant Rat protein expressed in E. coli.
Documents del producto
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) |
Host | E. coli |
Origin | Rat |
Conjugation | Unconjugated |
Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 90% |
Size 1 | 1 mg |
Size 2 | 5 mg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 1-2 months. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Background | Protein PPM1A |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Related Products

PPM1A antibody
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Ver Producto
Recombinant Human PPM1A
Ver Producto
Protein Phosphatase, Mg2+/Mn2+ Dependent 1A (PPM1A) Antibody
PPM1A Antibody is a Rabbit Polyclonal antibody against PPM1A. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Ver Producto