Rat Protein LCHN (DENND11) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DENND11
proveedor
Abbexareference
abx530795Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Protein LCHN (DENND11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Protein LCHN concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
DENN domain containing 11 (DENND11) is another member of the DENN family, functioning as a guanine nucleotide exchange factor (GEF) for Rab GTPases, with roles in vesicular trafficking and cellular organization. DENND11 is involved in regulating autophagy and endocytosis, contributing to the formation and maturation of autophagosomes and the recycling of endocytic vesicles. The DENN domain facilitates the activation of Rab GTPases by promoting GDP-GTP exchange, thereby modulating vesicular transport and membrane fusion events. DENND11 is highly expressed in certain tissues, particularly those with high vesicle trafficking demands, such as neuronal and epithelial cells. Mutations or dysregulation of DENND11 have been associated with neurological disorders and impaired autophagic flux, highlighting its role in maintaining cellular proteostasis and function.
Características del producto
category
ELISA Kits
immunogen target
Protein LCHN (DENND11)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
LCHN,PRO2561,KIAA1147,Protein LCHN
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DENND11
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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