Rat Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) CLIA Kit

Rat Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) CLIA Kit es un kit CLIA tipo Sandwich para su uso con suero, plasma, homogeneizados de tejido y otros fluidos biológicos.

Background

Platelet derived growth factor receptor like (PDGFRL) lacks intrinsic kinase activity and is thought to function in the regulation of extracellular matrix components and intercellular communication although its precise role is less defined compared to PDGFRA and PDGFRB mutations in PDGFRL have been linked to tumor suppressor activity in colorectal and gastric cancers suggesting it may act as a modulator of growth factor signaling networks its reduced expression has been correlated with increased tumor invasiveness and metastasis in some cancers indicating its potential importance in maintaining cellular homeostasis ongoing research seeks to clarify its role in cellular signaling and its impact on cancer progression and therapeutic resistance.