Rat Plasminogen Activator Inhibitor 2 (SERPINB2) CLIA Kit
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Description
Rat Plasminogen Activator Inhibitor 2 (PAI2 /SERPINB2) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Plasma.
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Plasminogen Activator Inhibitor 2 (SERPINB2) |
| Reactivity | Rat |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | < 0.57 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Plasma. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | PAI,PAI2,PAI-2,PLANH2,HsT1201,Plasminogen activator inhibitor 2,Monocyte Arg-serpin,Placental plasminogen activator inhibitor,Serpin B2 |
| Background | CLIA Kits SERPINB2 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
SERPINB2, also known as plasminogen activator inhibitor type 2 (PAI-2), is a member of the serine protease inhibitor (SERPIN) superfamily. This family of proteins is crucial for regulating proteolytic processes in various biological systems. Unlike its close relative PAI-1, which is primarily secreted into the extracellular space, SERPINB2 is predominantly found within the cytoplasm of cells, although it can also be secreted under certain conditions. SERPINB2 is encoded by the SERPINB2 gene located on chromosome 18q21.3 in humans. It is an acute-phase protein, meaning its expression is rapidly upregulated in response to inflammatory stimuli. SERPINB2 has been extensively studied due to its role in regulating fibrinolysis, the process by which blood clots are broken down. However, recent research has uncovered a broader range of functions for SERPINB2, including roles in immune regulation, apoptosis, and cellular differentiation
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