Rat Pgr(Progesterone receptor) ELISA Kit

Este producto es parte de PGR - progesterone receptor
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935106861
info@markelab.com
name
Rat Pgr(Progesterone receptor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0492

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Data sheet

Product specifications

CategoryELISA Kits
Reactivityrat
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich ELISA, Double Antibody
Test Range0.313-20ng/ml
Size 196T
Sample TypeSerum,Plasma,Tissue homogenates,Other biological fluids
AvailabilityShipped within 10-14 working days.
Storage2-8 °C for 6 months
UniProt IDQ63449
AliasPR,NR3C3,Nuclear receptor subfamily 3 group C member 3
BackgroundElisa Kits PGR
StatusRUO

Progesterone receptor (PGR) is a nuclear receptor that mediates the effects of progesterone, a steroid hormone involved in regulating the female reproductive system and various physiological processes PGR plays a key role in processes such as the menstrual cycle, pregnancy, and embryogenesis It functions by binding to progesterone, which activates the receptor and induces changes in gene expression that control cell differentiation, apoptosis, and immune responses During pregnancy, PGR helps maintain uterine function and supports the development of the fetus In the menstrual cycle, it helps regulate the endometrial lining, preparing it for implantation of a fertilized egg In addition, PGR is involved in the regulation of breast tissue, where its activation is essential for mammary gland development and function Dysregulation of PGR signaling has been associated with various diseases, including hormone-driven cancers like breast cancer and endometrial cancer, where altered progesterone signaling contributes to tumor growth and progression PGR is also a target for therapies such as progestins used in birth control and hormone replacement therapies

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Progesterone Receptor (PGR) Antibody

PGR Antibody is a Rabbit Polyclonal antibody against PGR. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

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