Rat Nucleoporin P58/p45 (NUP58) ELISA Kit

Este producto es parte de NUP - nucleoporin
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Nucleoporin P58/p45 (NUP58) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx536307
tested applications
ELISA

Description

Rat Nucleoporin P58/p45 (NUP58) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Nucleoporin p58/p45 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Nucleoporin P58/p45 (NUP58)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P70581
Alias
NUP45,NUPL1,PRO2463,58 kDa nucleoporin,Nucleoporin-like protein 1
Background
Elisa kits for NUP58
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Nucleoporin 58 (NUP58) is a significant component of the nuclear pore complex, contributing to the transport of large macromolecules, including RNA and proteins, between the nucleus and the cytoplasm It helps regulate nuclear-cytoplasmic exchange by interacting with other nucleoporins to form the structural framework of the nuclear pore complex NUP58 plays a crucial role in the passage of molecules required for cellular processes such as gene expression, protein synthesis, and cell signaling Its involvement in RNA and ribosomal subunit transport is vital for ensuring efficient protein synthesis, which is necessary for cellular function NUP58 also has roles in regulating cellular stress responses and supporting cell division by maintaining the integrity of nuclear pore transport Dysregulation of NUP58 has been implicated in a variety of diseases, including cancer, where malfunctioning nucleocytoplasmic transport can contribute to tumor progression and metastasis Furthermore, NUP58 helps sustain cellular homeostasis by ensuring that key molecules are correctly localized within the nucleus or cytoplasm, making it an essential player in cellular function

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