Rat Nucleoporin 50 (NUP50) ELISA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Rat Nucleoporin 50 (NUP50) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Nuclear pore complex protein Nup50 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nucleoporin 50 (NUP50) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O08587 |
| Alias | NPAP60,NPAP60L,nucleoporin 50kDa,Nuclear pore-associated protein 60 kDa-like |
| Background | Elisa kits for NUP50 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nucleoporin 50 (NUP50) is another key nucleoporin involved in the transport of proteins and RNA across the nuclear envelope NUP50 functions as a shuttle protein in the process of nuclear import, facilitating the recycling of importin proteins, which are required for the delivery of cargo molecules into the nucleus It is involved in the release of cargo from importins at the nuclear pore and aids in the efficient transport of proteins involved in various cellular processes such as signal transduction, gene regulation, and DNA repair NUP50’s role in nuclear import is crucial for maintaining cellular function, as defects in this process can lead to impaired gene expression, cell cycle progression, and protein localization Dysregulation of NUP50 has been implicated in diseases such as cancer, where alterations in nuclear import and protein trafficking contribute to tumor progression and metastasis
Related Products
NUP50 antibody
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Ver Producto
Nucleoporin 50 (NUP50) Antibody
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.
Ver Producto
Nucleoporin 50 (NUP50) Antibody
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. This antibody is supplied as crude ascites.
Ver Producto