Rat Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) ELISA Kit
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Description
Rat Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2)
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | RVR,BD73,EAR-1R,REVERBB,REVERBbeta,Rev-erb alpha-related receptor,V-erbA-related protein 1-related |
| Background | Elisa kits for NR1D2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nuclear receptor subfamily 1 group D member 2 (NR1D2), also known as Rev-Erbβ, is a closely related homolog of NR1D1, and it also plays a crucial role in regulating circadian rhythms and metabolic homeostasis NR1D2 is involved in controlling the expression of genes that regulate the body’s internal clock, metabolism, and immune responses Similar to NR1D1, NR1D2 acts by repressing the transcription of target genes through binding to specific DNA elements, influencing lipid and glucose metabolism, and modulating inflammatory responses NR1D2 is highly expressed in tissues such as the liver, skeletal muscle, and adipose tissue, where it helps control circadian variations in metabolism and energy expenditure Dysregulation of NR1D2 has been associated with metabolic disorders, including obesity, type 2 diabetes, and fatty liver disease, as well as inflammation-related conditions like autoimmune diseases and cardiovascular disorders In addition to its role in metabolism and immune function, NR1D2’s participation in regulating the circadian rhythm highlights its potential therapeutic value for managing disorders related to disrupted biological clocks, such as sleep disturbances and shift work-induced metabolic abnormalities
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