Rat Neuritin 1 (NRN1) Protein

Product specifications

Proteins and Peptides

Neuritin 1 (NRN1)

E. coli

Rat

Unconjugated

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Please enquire.

Tag: N-terminal His tag

Recombinant

> 90%

1 mg

5 mg

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

WB, SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Shipped within 1-2 months.

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

No

O08957

NRN

Protein NRN1

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Neuritin 1 (NRN1) is a protein encoded by the NRN1 gene and plays a significant role in neural development, synaptic plasticity, and neuronal regeneration, being highly expressed in the brain, particularly in regions associated with neurogenesis such as the hippocampus and cerebral cortex. It is induced by neural activity and neurotrophic factors, mediating processes like axonal growth, dendritic arborization, and synaptogenesis, which are crucial for learning and memory. NRN1 acts as a glycosylphosphatidylinositol (GPI)-anchored protein on the neuronal membrane, influencing cell-cell interactions and extracellular signaling, particularly in response to stimuli like injury or ischemic events. Dysregulation of NRN1 expression has been linked to neurodegenerative disorders and psychiatric conditions such as Alzheimer's disease, schizophrenia, and depression, indicating its role in maintaining neural integrity and adaptability. In experimental models, NRN1 has shown potential in promoting axonal regeneration and functional recovery following nerve injury, highlighting its therapeutic relevance. Elevated NRN1 expression correlates with increased neuronal survival and plasticity, while its suppression can impair cognitive and motor functions, illustrating its pivotal role in sustaining neurophysiological processes

Related Products

Human NRN1 (Neuritin) ELISA Kit

Ver Producto

Human Neuritin (NRN1) ELISA Kit

Human Neuritin (NRN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neuritin concentrations in tissue homogenates, cell lysates and other biological fluids.

Ver Producto

Cow Neuritin (NRN1) ELISA Kit

Cow Neuritin (NRN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Neuritin concentrations in tissue homogenates, cell lysates and other biological fluids.

Ver Producto