Rat N-Acetylgalactosaminidase Alpha (NAGA) Protein

Este producto es parte de NAGA-N-Acetylgalactosaminidase Alpha
Rat N-Acetylgalactosaminidase Alpha (NAGA) Protein

Pida mas información

935106861

info@markelab.com

Precio

247€ (10 µg)

Protein NAGA

proveedor

Abbexa

reference

abx068198

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

N-Acetylgalactosaminidase Alpha (NAGa) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

N-Acetylgalactosaminidase Alpha (NAGA) is an enzyme involved in the breakdown of complex carbohydrates. catalyzes the hydrolysis of terminal alpha-N-acetylgalactosaminyl residues in glycoproteins and glycolipids (lysosomes), Deficiency in NAGA enzyme activity leads to a rare genetic disorder known as Schindler disease, which is characterized by the accumulation of certain glycoproteins and glycolipids in lysosomes. Schindler disease can manifest in different forms, including Schindler disease type I and type II, depending on the severity of the enzyme deficiency. Symptoms of Schindler disease can vary widely but may include developmental delay, intellectual disability, seizures, skeletal abnormalities, and other neurological and systemic manifestations. The severity and progression of the disease can also vary, ranging from mild to severe.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

N-Acetylgalactosaminidase Alpha (NAGA)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 24.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu18-Asp217 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

NAGA


dry ice

No


availability

Shipped within 5-12 working days.


alias

GALB, D22S674


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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clonality

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