Rat Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit

Este producto es parte de MYLK - myosin light chain kinase
Rat Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits MYLK3

proveedor

Abbexa

reference

abx534198

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Myosin Light Chain Kinase 3 (MYLK3) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

Myosin light chain kinase 3 (MYLK3) is primarily expressed in cardiac muscle, where it plays a pivotal role in modulating heart muscle contraction and relaxation. Similar to MYLK2, MYLK3 phosphorylates the regulatory light chains of myosin II, facilitating efficient cross-bridge cycling and force production during cardiac cycles. MYLK3's activity is also dependent on calcium-calmodulin signaling, linking it to the intracellular calcium fluxes that drive cardiac contractility. MYLK3 is essential for maintaining myocardial function and is implicated in cardiac hypertrophy and heart failure when dysregulated. Emerging research highlights MYLK3's involvement in sarcomere organization and its potential as a therapeutic target for improving cardiac performance in disease settings. Together, MYLK2 and MYLK3 underscore the critical and tissue-specific roles of myosin light chain kinases in muscle physiology.

Características del producto

category

ELISA Kits


immunogen target

Myosin Light Chain Kinase 3 (MYLK3)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.07 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Serum,Plasma,Tissue homogenates,Other biological fluids


size 1

96 tests


alias

MLCK,MLCK2,caMLCK,Cardiac-MyBP-C-associated Ca/CaM kinase,Cardiac-MLCK


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

MYLK3


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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