Rat Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit
![Rat Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit](/_next/image?url=https%3A%2F%2Fmarkelab.com%2Fpublic-files%2Fimages%2FELISA-box.webp&w=3840&q=75)
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits MYLK3
proveedor
Abbexareference
abx534198Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Myosin Light Chain Kinase 3 (MYLK3) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
Myosin light chain kinase 3 (MYLK3) is primarily expressed in cardiac muscle, where it plays a pivotal role in modulating heart muscle contraction and relaxation. Similar to MYLK2, MYLK3 phosphorylates the regulatory light chains of myosin II, facilitating efficient cross-bridge cycling and force production during cardiac cycles. MYLK3's activity is also dependent on calcium-calmodulin signaling, linking it to the intracellular calcium fluxes that drive cardiac contractility. MYLK3 is essential for maintaining myocardial function and is implicated in cardiac hypertrophy and heart failure when dysregulated. Emerging research highlights MYLK3's involvement in sarcomere organization and its potential as a therapeutic target for improving cardiac performance in disease settings. Together, MYLK2 and MYLK3 underscore the critical and tissue-specific roles of myosin light chain kinases in muscle physiology.
Características del producto
category
ELISA Kits
immunogen target
Myosin Light Chain Kinase 3 (MYLK3)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96 tests
alias
MLCK,MLCK2,caMLCK,Cardiac-MyBP-C-associated Ca/CaM kinase,Cardiac-MLCK
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
MYLK3
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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