Rat Metalloproteinase Inhibitor 1 (TIMP1) ELISA Kit

Este producto es parte de TIMP1- Metalloproteinase Inhibitor 1
Rat Metalloproteinase Inhibitor 1 (TIMP1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

487.5€ (96 tests)

Elisa kits for TIMP1

proveedor

Abbexa

reference

abx050215

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Metalloproteinase Inhibitor 1 (TIMP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Metalloproteinase Inhibitor 1 (TIMP1) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

TIMP1 is a member of the TIMP family and acts as a natural inhibitor of matrix metalloproteinases (MMPs), which are enzymes that degrade components of the extracellular matrix TIMP1 regulates tissue remodeling, inflammation, and wound healing by inhibiting MMP activity and preventing excessive matrix breakdown It also exhibits anti-apoptotic properties by binding to cell surface receptors and activating survival pathways TIMP1 plays a role in cancer progression where its overexpression can inhibit tumor invasion and metastasis by limiting MMP activity, while paradoxically, it can also promote tumor growth by stimulating cell proliferation and angiogenesis Dysregulation of TIMP1 is observed in diseases such as fibrosis, cardiovascular disease, and chronic inflammatory conditions, where altered MMP activity contributes to tissue damage and remodeling TIMP1’s dual role as a regulator of extracellular matrix turnover and cell signaling makes it a key player in both normal physiological processes and pathological conditions

Características del producto

category

ELISA Kits


immunogen target

Metalloproteinase Inhibitor 1 (TIMP1)


reactivity

Rat


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

< 3 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


size 1

96 tests


alias

Tissue inhibitor of metalloproteinases 1,EPA,EPO,HCI,CLGI,TIMP,TIMP-1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TIMP1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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