Rat Membrane Cofactor Protein (CD46) ELISA Kit
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935106861
info@markelab.com
Precio
556.25€ (96 tests)
Elisa Kits CD46
proveedor
Abbexareference
abx516180Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Membrane Cofactor Protein (CD46) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Membrane Cofactor Protein (CD46) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CD46, also known as membrane cofactor protein (MCP), is a transmembrane glycoprotein that serves primarily as a regulatory component of the complement system, protecting host cells from complement-mediated damage. CD46 is widely expressed on almost all nucleated cells and plays a key role in immune regulation, ensuring that the complement system, which is responsible for clearing pathogens, does not attack the body’s own cells. CD46 does this by serving as a cofactor for the proteolytic cleavage of C3b and C4b, two crucial components of the complement pathway, which are inactivated by factor I. In addition to its role in the complement system, CD46 is involved in various immune functions, including modulation of T-cell responses, immune tolerance, and viral entry. Several viruses, such as the measles virus and human herpesvirus 6 (HHV-6), use CD46 as a receptor to gain entry into host cells, highlighting its involvement in viral pathogenesis.
Características del producto
category
ELISA Kits
immunogen target
Membrane Cofactor Protein (CD46)
reactivity
Rat
test range
31.2 pg/ml - 2000 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
MCP,TLX,AHUS2,MIC10,TRA2.10,Membrane cofactor protein,Trophoblast leukocyte common antigen
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CD46
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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