Rat Melanocortin Receptor 3 (MC3R) ELISA Kit
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935106861
info@markelab.com
Precio
611€ (96 tests)
Elisa kits for MC3R
proveedor
Abbexareference
abx354241Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Melanocortin Receptor 3 (MC3R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Melanocortin Receptor 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
MC3R is a G protein-coupled receptor activated by melanocortins, including α-MSH, β-MSH, and ACTH. MC3R is expressed primarily in the hypothalamus, pituitary gland, and other peripheral tissues, where it plays a critical role in energy homeostasis, feeding behavior, and circadian rhythms. MC3R signaling involves coupling to Gs proteins, leading to increased cAMP levels and activation of downstream pathways that regulate appetite suppression and energy expenditure. In the hypothalamus, MC3R modulates the activity of neuropeptides, such as AgRP and POMC, balancing food intake and energy utilization. Dysregulation of MC3R has been linked to obesity, metabolic syndrome, and circadian rhythm disorders. MC3R also contributes to immune regulation, influencing anti-inflammatory responses and macrophage function. Emerging evidence highlights its role in skeletal muscle metabolism and cardiovascular function. Therapeutic targeting of MC3R is being explored for obesity treatment, metabolic disorders, and inflammatory conditions, emphasizing its importance in energy balance and homeostatic regulation.
Características del producto
category
ELISA Kits
immunogen target
Melanocortin Receptor 3 (MC3R)
reactivity
Rat
test range
78 pg/ml - 5000 pg/ml
sensitivity
46.9 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
MC3R,BMIQ9,MC3,MC3-R,OB20,OQTL,γ-MSH receptor,melanocortin receptor 3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MC3R
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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