Rat Macrosialin (CD68) Protein
1235€ (100 µg)
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935106861
info@markelab.com
name
Rat Macrosialin (CD68) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691214
tested applications
SDS-PAGE
Description
Rat CD68 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat CD68 (Q4FZY1) (Met1-Ser295) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CD68 |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: 56.5 kDa Sequence Fragment: Met1-Ser295 Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q4FZY1 |
| Alias | GP110,LAMP4,SCARD1,Macrosialin |
| Background | Protein CD68 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD68 is a glycoprotein primarily expressed by cells of the monocyte/macrophage lineage. It belongs to the family of lysosomal-associated membrane proteins (LAMPs) and is widely used as a marker for macrophages, monocytes, dendritic cells, and other myeloid lineage cells. Although CD68 is predominantly associated with immune system cells, it is also found in some non-hematopoietic tissues and other cell types under certain conditions, such as fibroblasts and endothelial cells. This broad expression pattern supports its diverse role in cellular processes like phagocytosis, cell adhesion, and antigen presentation. CD68 is heavily involved in macrophage biology, specifically in processes like scavenging cellular debris, tissue remodeling, and immune surveillance. This protein plays a significant role in the clearance of pathogens and apoptotic cells, contributing to immune homeostasis. It is mainly located in lysosomes and endosomes, though it can also be present on the plasma membrane.
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