Rat Fc Epsilon Receptor Ii (FCER2) Protein

Este producto es parte de FCER2 - Fc epsilon receptor II
Rat Fc Epsilon Receptor Ii (FCER2) Protein
1118€ (100 µg)

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Name
Rat Fc Epsilon Receptor Ii (FCER2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx693066
Tested Applications
SDS-PAGE

Description

Fc Epsilon Receptor Ii (FCER2) protein is a recombinant Rat protein expressed in HEK293 cells.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Fc Epsilon Receptor Ii (FCER2)
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Glu50-Pro331
Tag: N-terminal Fc tag
Origin
Rat
Observed MW
60.2 kDa
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: Sterile PBS, PH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
Q6AZ45
Alias
CD23,FCE2,CD23A,IGEBF,CLEC4J,FCErII,BLAST-2,Low affinity immunoglobulin epsilon Fc receptor,C-type lectin domain family 4 member J,Fc-epsilon-RII,Immunoglobulin E-binding factor,Lymphocyte IgE receptor
Background
Protein FCER2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Background

FCER2, also known as CD23, is a low-affinity receptor for the Fc region of Immunoglobulin E (IgE). It is an important protein involved in the regulation of IgE-mediated immune responses and plays a key role in allergy, asthma, and immune regulation. FCER2 was first recognized for its role in B cell differentiation and later found to be expressed in several other immune cell types, including monocytes, eosinophils, dendritic cells, and macrophages. The interaction of CD23 with IgE is critical in the regulation of IgE levels and in modulating allergic responses. Unlike Fc epsilon receptor I (FCERI), which is a high-affinity receptor for IgE and is found on mast cells and basophils, CD23 has a much lower affinity for IgE and is expressed predominantly on B cells. This difference in affinity and cellular distribution allows CD23 to play a different role in immune regulation, particularly in controlling the production of IgE and mediating the interaction between IgE and antigen-presenting cells.

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