Rat Leukemia Inhibitory Factor Receptor (LIFR) ELISA Kit

Este producto es parte de LIFR - LIF receptor subunit alpha
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624€ (96 tests)

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935106861
info@markelab.com
name
Rat Leukemia Inhibitory Factor Receptor (LIFR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx255788
tested applications
ELISA

Description

Rat Leukemia Inhibitory Factor Receptor (LIFR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Leukemia Inhibitory Factor Receptor concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetLeukemia Inhibitory Factor Receptor (LIFR)
ReactivityRat
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.31 ng/ml - 20 ng/ml
Sensitivity0.19 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDO70535
Gene ID81680
AliasLeukemia inhibitory factor receptor,SWS,SJS2,STWS,CD118,LIF-R,LIF receptor
BackgroundElisa kits for LIFR
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

The leukemia inhibitory factor receptor (LIFR), also known as the LIF receptor subunit alpha, is a component of a cytokine receptor complex responsible for mediating the effects of the leukemia inhibitory factor (LIF). LIF is part of the interleukin-6 (IL-6) family of cytokines and is involved in various cellular processes, such as cell survival, proliferation, and differentiation, particularly in neuronal, hematopoietic, and reproductive cells. LIFR is encoded by the LIFR gene, located on chromosome 5p13, and is widely expressed across various tissues, including the placenta, brain, liver, and bone marrow. LIFR functions as a non-signaling receptor subunit and, upon binding to LIF, associates with the co-receptor gp130. Together, this receptor complex initiates intracellular signaling pathways that are central to immune responses, tissue repair, and neural development. LIFR is significant in embryonic development and stem cell maintenance, and dysregulation of LIFR signaling is associated with several diseases, such as inflammatory disorders, cancer, and neurodegenerative diseases.

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