Rat Lactate Dehydrogenase A (LDHA) Protein

Este producto es parte de LDHA - Lactate Dehydrogenase A
Rat Lactate Dehydrogenase A (LDHA) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein LDHA

proveedor

Abbexa

reference

abx067673

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Lactate Dehydrogenase A (LDHA) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

Lactate Dehydrogenase A (LDHA) is an enzyme that catalyzes the conversion of pyruvate to lactate in the final step of anaerobic glycolysis. LDHA plays a critical role in cellular energy metabolism, especially under hypoxic conditions, where it helps regenerate NAD+ for glycolysis. It is highly expressed in tissues with high glycolytic activity, such as skeletal muscle. In cancer, LDHA is upregulated as part of the Warburg effect, where tumor cells preferentially use glycolysis for energy production, even in the presence of oxygen. Elevated LDHA expression is associated with tumor growth, metastasis, and resistance to therapy, making it a target for anticancer therapies. Beyond cancer, LDHA is implicated in metabolic disorders and muscular diseases, highlighting its importance in both normal physiology and pathological conditions.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Lactate Dehydrogenase A (LDHA)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 38 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Phe332 Tag: N-terminal His tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

LDHA


dry ice

No


availability

Shipped within 5-12 working days.


alias

LDHM, GSD11,PIG1,HEL-S-133P,lactate Dehydrogenase A,prolifeRation-inducing gene 19


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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