Rat Lactate Dehydrogenase A (LDHA) Protein
221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Lactate Dehydrogenase A (LDHA) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067673
tested applications
WB, SDS-PAGE
Description
Lactate Dehydrogenase A (LDHA) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Lactate Dehydrogenase A (LDHA) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 38 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Phe332 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04642 |
| Alias | LDHM, GSD11,PIG1,HEL-S-133P,lactate Dehydrogenase A,prolifeRation-inducing gene 19 |
| Background | Protein LDHA |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Lactate Dehydrogenase A (LDHA) is an enzyme that catalyzes the conversion of pyruvate to lactate in the final step of anaerobic glycolysis. LDHA plays a critical role in cellular energy metabolism, especially under hypoxic conditions, where it helps regenerate NAD+ for glycolysis. It is highly expressed in tissues with high glycolytic activity, such as skeletal muscle. In cancer, LDHA is upregulated as part of the Warburg effect, where tumor cells preferentially use glycolysis for energy production, even in the presence of oxygen. Elevated LDHA expression is associated with tumor growth, metastasis, and resistance to therapy, making it a target for anticancer therapies. Beyond cancer, LDHA is implicated in metabolic disorders and muscular diseases, highlighting its importance in both normal physiology and pathological conditions.
Related Products
Human LDHA (L-lactate dehydrogenase A chain) ELISA Kit
Ver Producto
LDHA antibody
Ver Producto