Rat Junctional Adhesion Molecule 3 (JAM3) ELISA Kit
715€ (96 tests)
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name
Rat Junctional Adhesion Molecule 3 (JAM3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx528941
tested applications
ELISA
Description
Rat Junctional Adhesion Molecule 3 (JAM3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Junctional Adhesion Molecule 3 (JAM3) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Junctional Adhesion Molecule 3 (JAM3) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q68FQ2 |
| Alias | JAMC,JAM-2,JAM-3,JAM-C,Junctional adhesion molecule C |
| Background | Elisa kits for JAM3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
JAM3 is predominantly expressed in endothelial cells, platelets, and certain subsets of immune cells. Like JAM2, it features two extracellular Ig-like domains, a single transmembrane domain, and a cytoplasmic tail that interacts with scaffolding proteins to organize tight junctions. JAM3 plays a critical role in endothelial cell adhesion and platelet aggregation, as well as in the regulation of vascular permeability and angiogenesis. It interacts with other adhesion molecules, such as JAM2 and integrins, to mediate cell-cell interactions and leukocyte trafficking during immune responses. Additionally, JAM3 is essential for maintaining the integrity of the blood-brain barrier and regulating cell migration in response to injury or inflammation.
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