Rat Interleukin 3 (IL3) Protein
247€ (10 µg)
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935106861
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name
Rat Interleukin 3 (IL3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069743
tested applications
WB, SDS-PAGE
Description
Rat IL3 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 3 (IL3) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 45.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile27-Cys166 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04823 |
| Alias | IL-3,MCG, MULTI-CSF,Hematopoietic growth factor,Mast cell growth factor,MCGF,Multipotential colony-stimulating factor,P-cell-stimulating factor |
| Background | Protein IL3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin-3 (IL3) is a cytokine, a type of signaling protein involved in regulating immune and hematopoietic (blood cell formation) responses. Cytokines are crucial to the communication between cells, particularly within the immune system, helping to modulate the body's responses to pathogens, trauma, and inflammation. IL-3 is produced primarily by activated T cells, but also by other cells including mast cells, eosinophils, and monocytes, especially in response to immune challenges. Its primary function is to regulate the growth, differentiation, and survival of pluripotent hematopoietic stem cells, as well as various lineages of blood cells, making it a key player in hematopoiesis (the formation of blood cellular components). IL-3 is important not only in normal immune responses but also in pathological conditions such as allergies, autoimmune disorders, and cancers. The signaling cascade initiated by IL-3 involves several pathways, including the JAK/STAT (Janus kinase/Signal transducers and activators of transcription) and PI3K (Phosphoinositide 3-kinase)/AKT pathways, which contribute to the proliferation and survival of various cell types
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