Rat Interleukin 27A (IL27A) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
702€ (96 tests)
Elisa kits for IL27
proveedor
Abbexareference
abx155731Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Interleukin 27A (IL27A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat IL27A concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Interleukin 27A (IL27A)
Background
Interleukin 27 (IL27) is a heterodimeric cytokine that belongs to the IL-12 cytokine family and plays a pivotal role in regulating immune responses. IL-27 is produced primarily by antigen-presenting cells (APCs), such as dendritic cells, macrophages, and monocytes, following activation by various pathogen-associated signals. Its primary function is to modulate T cell responses, particularly by promoting the differentiation of T helper 1 (Th1) cells while simultaneously limiting excessive inflammatory responses through immune suppression. This dual role positions IL-27 as a key regulator of both pro-inflammatory and anti-inflammatory immune responses. IL-27 is composed of two distinct subunits: EBI3 (Epstein-Barr virus-induced gene 3) and p28, which together form the functional cytokine. IL-27 signals through a heterodimeric receptor composed of IL-27R (WSX-1) and gp130, activating a range of signaling pathways that control immune function, including the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway.
Características del producto
category
ELISA Kits
immunogen target
Interleukin 27A (IL27A)
reactivity
Rat
test range
7.8 pg/ml - 500 pg/ml
sensitivity
< 3.1 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
p28,IL30,IL-27,IL27A,IL-27A,IL27p28,IL-27 subunit alpha,IL-27-A,Interleukin-30,p28
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
IL27
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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