Rat Interleukin-21 Receptor (IL21R) Protein (Active)

1118€ (100 µg)
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935106861
info@markelab.com
name
Rat Interleukin-21 Receptor (IL21R) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx692430
tested applications
SDS-PAGE
Description
Interleukin-21 Receptor (IL21R) protein is a recombinant Rat protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin-21 Receptor (IL21R) |
| Host | HEK293 cells |
| Assay Type | Activity: Active Sequence Fragment: Met1-Pro236 Tag: C-terminal His tag |
| Origin | Rat |
| Observed MW | 26.5 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q5EBB1 |
| Alias | NILR,CD360,IMD56,IL-21 receptor,IL-21R,Novel interleukin receptor |
| Background | Protein IL21R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Interleukin 21 receptor (IL21R) is a member of the cytokine receptor superfamily, specifically involved in immune cell communication and regulation. IL21R binds interleukin-21 (IL-21), a cytokine that plays crucial roles in immune response modulation, primarily impacting the activity of T cells, B cells, and natural killer (NK) cells. IL-21/IL21R signaling is essential for adaptive immunity, supporting the differentiation, proliferation, and functional enhancement of immune cells. This receptor is expressed on a wide range of cells within the immune system, including T and B lymphocytes, NK cells, dendritic cells, and some epithelial cells. Given its immunoregulatory functions, IL21R signaling has implications in autoimmunity, cancer immunology, and chronic inflammatory conditions.


