Rat Interleukin 12B (IL12B) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
587.5€ (96 tests)
Elisa Kits IL12B
proveedor
Abbexareference
abx255755Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Interleukin 12B (IL12B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Interleukin 12 p40 concentrations in serum, plasma and other biological fluids.
Background
Interleukin 12 beta (IL12B), also referred to as IL-12p40, is another key subunit of interleukin-12 and is critical for immune regulation and pathogen defense. IL12B pairs with IL12A to form IL-12 or with IL23A to form IL-23, a related cytokine involved in promoting inflammation and autoimmunity. Produced primarily by antigen-presenting cells in response to microbial infections or inflammatory stimuli, IL12B drives the differentiation of naïve CD4+ T-cells into Th1 cells, promoting IFN-γ secretion and enhancing immune responses against intracellular pathogens. Genetic variations in IL12B have been linked to increased susceptibility to autoimmune disorders, such as psoriasis and inflammatory bowel disease (IBD). As a result, IL12B is a target of therapeutic interest in immune-mediated diseases, and IL-12/IL-23 inhibitors have been developed to treat conditions like psoriasis and Crohn's disease. Understanding the intricate regulation and functional roles of IL12B remains a priority in immunological research.
Características del producto
category
ELISA Kits
immunogen target
Interleukin 12B (IL12B)
reactivity
Rat
test range
12.5 pg/ml - 800 pg/ml
sensitivity
7.5 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Other biological fluids
size 1
96 tests
alias
CLMF,NKSF,CLMF2,IMD28,IMD29,NKSF2,IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
IL12B
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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