Rat Intercellular Adhesion Molecule 2 / CD102 (ICAM2) ELISA Kit

Este producto es parte de ICAM2 - intercellular adhesion molecule 2
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611€ (96 tests)

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935106861
info@markelab.com
name
Rat Intercellular Adhesion Molecule 2 / CD102 (ICAM2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx054295
tested applications
ELISA

Description

Rat Intercellular Adhesion Molecule 2 / CD102 (ICAM2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Intercellular Adhesion Molecule 2 / CD102 (ICAM2) concentrations in serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetIntercellular Adhesion Molecule 2 / CD102 (ICAM2)
ReactivityRat
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range31.2 pg/ml - 2000 pg/ml
Sensitivity18.8 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeSerum, plasma and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasIntercellular adhesion molecule 2,CD102,ICAM-2
BackgroundElisa kits for ICAM2
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Intercellular adhesion molecule 2 (ICAM2) is a member of the immunoglobulin superfamily and plays an essential role in immune cell trafficking, endothelial integrity, and cell signaling. ICAM-2 is encoded by the ICAM2 gene and, along with other intercellular adhesion molecules, serves as a ligand for leukocyte integrins such as LFA-1 (lymphocyte function-associated antigen-1), facilitating the adhesion and transmigration of leukocytes across endothelial cells. It is broadly expressed on endothelial cells, leukocytes, and various other cell types. ICAM-2 is involved in vascular and immune system homeostasis, with roles extending to inflammation, cancer, and neurological functions. Unlike ICAM-1, which is inducible by inflammatory cytokines, ICAM-2 is constitutively expressed but has been found to increase in certain pathophysiological conditions, especially involving endothelial activation. The stable presence of ICAM-2 on endothelial cells makes it significant for lymphocyte recirculation and endothelial-leukocyte interactions, aiding immune surveillance and response to pathogens.

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