Rat Insulin Like Growth Factor 1 Receptor (IGF1R) CLIA Kit

Rat Insulin Like Growth Factor 1 Receptor (IGF1R) CLIA Kit is a Sandwich CLIA Kit for use with Tissue homogenates, cell lysates and other biological fluids.

Background

The insulin-like growth factor 1 receptor (IGF1R) is a transmembrane receptor that plays a crucial role in cellular growth, survival, and metabolism. It is activated primarily by insulin-like growth factor 1 (IGF-1), a hormone structurally similar to insulin but with distinct biological functions. IGF1R is a member of the receptor tyrosine kinase (RTK) family, which includes receptors like the insulin receptor (INSR). IGF1R signaling is essential for normal development and is involved in many physiological processes, such as cell differentiation, proliferation, and apoptosis inhibition. This receptor is also significant in pathological states, especially cancer, where it can drive tumor growth and metastasis through enhanced cell survival and proliferation pathways.