Rat Importin Subunit Alpha-6 (KPNA5) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for KPNA5
proveedor
Abbexareference
abx528300Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Importin Subunit Alpha-6 (KPNA5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Importin subunit alpha-6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
KPNA5, or importin-α6, functions as an adaptor protein mediating the nuclear import of cargo proteins containing classical nuclear localization signals (NLS). It forms a heterodimer with importin-β to translocate proteins across the nuclear pore complex (NPC) in an energy-dependent manner. KPNA5 is predominantly expressed in the brain, testes, and immune cells, suggesting specialized roles in neuronal function, germ cell development, and immune regulation. It regulates nuclear import of transcription factors and signaling proteins involved in cell differentiation, stress responses, and viral replication. KPNA5 is implicated in neurodevelopmental disorders and cancers, where it modulates nuclear transport of growth and survival regulators. Functional studies demonstrate its critical role in maintaining nuclear transport specificity and cellular homeostasis during development and disease progression.
Características del producto
category
ELISA Kits
immunogen target
Importin Subunit Alpha-6 (KPNA5)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
IPOA6,SRP6,Importin subunit alpha-6
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
KPNA5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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