Rat Importin Subunit Alpha-6 (KPNA5) ELISA Kit

Este producto es parte de KPNA - karyopherin subunit alpha
Rat Importin Subunit Alpha-6 (KPNA5) ELISA Kit
715€ (96 tests)

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Name
Rat Importin Subunit Alpha-6 (KPNA5) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx528300
Tested Applications
ELISA

Description

Rat Importin Subunit Alpha-6 (KPNA5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Importin subunit alpha-6 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Importin Subunit Alpha-6 (KPNA5)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q56R16
Alias
IPOA6,SRP6,Importin subunit alpha-6
Background
Elisa Kits for: KPNA5
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

KPNA5, or importin-α6, functions as an adaptor protein mediating the nuclear import of cargo proteins containing classical nuclear localization signals (NLS). It forms a heterodimer with importin-β to translocate proteins across the nuclear pore complex (NPC) in an energy-dependent manner. KPNA5 is predominantly expressed in the brain, testes, and immune cells, suggesting specialized roles in neuronal function, germ cell development, and immune regulation. It regulates nuclear import of transcription factors and signaling proteins involved in cell differentiation, stress responses, and viral replication. KPNA5 is implicated in neurodevelopmental disorders and cancers, where it modulates nuclear transport of growth and survival regulators. Functional studies demonstrate its critical role in maintaining nuclear transport specificity and cellular homeostasis during development and disease progression.

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