Rat IL-12/p40(Interleukin 12 p40) ELISA Kit

Este producto es parte de IL12A - interleukin 12A
Rat IL-12/p40(Interleukin 12 p40) ELISA Kit

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935106861

info@markelab.com

Precio

Precio a consultar

Elisa Kits IL12A

proveedor

FineTest

reference

ER1087

Tested Applications

reactivity

rat

status

RUO

clonality


Background

Interleukin 12A (IL12A) is a subunit of the heterodimeric cytokine interleukin-12, which plays a pivotal role in the immune system by bridging innate and adaptive immunity. IL12A, also known as IL-12p35, pairs with the IL12B subunit (IL-12p40) to form the active cytokine IL-12, which is essential for inducing T-helper 1 (Th1) immune responses. IL12A is produced by activated antigen-presenting cells, such as macrophages and dendritic cells, in response to infections or immune challenges. It functions by stimulating natural killer (NK) cells and CD4+ T-cells to produce interferon-gamma (IFN-γ), a cytokine critical for pathogen clearance and enhancing cytotoxic activities. Dysregulation of IL12A expression has been associated with autoimmune diseases, chronic inflammation, and cancer. Therapeutic strategies targeting IL12A, including IL-12 inhibitors or engineered cytokines, are being explored for managing these conditions and for enhancing anti-tumor immune responses.

Características del producto

category

ELISA Kits


reactivity

rat


test range

11.719-750pg/ml


assay type

Sandwich ELISA, Double Antibody


assay data

Quantitative


detection method

Colorimetric


sample type

Serum,Plasma,Tissue homogenates,Other biological fluids


size 1

96T


alias

P35,CLMF,NFSK,NKSF1,IL-12A,Cytotoxic lymphocyte maturation factor 35 kDa subunit,CLMF p35,IL-12 subunit p35,NK cell stimulatory factor chain 1 


storage

2-8 °C for 6 months


or code

IL12A


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