Rat HYOU1 (Hypoxia Up Regulated 1) QuickTest ELISA Kit

Product Graph
Contáctenos para saber el precio

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Rat HYOU1 (Hypoxia Up Regulated 1) QuickTest ELISA Kit
category
ELISA Kits
provider
FineTest
reference
QT-ER1061
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Rat
Assay Data
120 minutes
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q63617
Alias
Hypoxia up-regulated protein 1, 150 kDa oxygen-regulated protein, ORP-150, 170 kDa glucose-regulated protein, GRP-170, HYOU1, GRP170, ORP150
Background
Elisa kits for HYOU1
Status
RUO

Related Products

EH3246

Human HYOU1 (Hypoxia Up Regulated 1) ELISA Kit

Ver Producto
ER1061

Rat HYOU1 (Hypoxia Up Regulated 1) ELISA Kit

Ver Producto
FNab10247

HYOU1 antibody

The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants.

Ver Producto