Rat Fibroblast Growth Factor Receptor 1 (FGFR1) ELISA Kit

Este producto es parte de FGFR1 - fibroblast growth factor receptor 1
Rat Fibroblast Growth Factor Receptor 1 (FGFR1) ELISA Kit

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935106861

info@markelab.com

Precio

525€ (96 tests)

Elisa Kits FGFR1

proveedor

Abbexa

reference

abx256921

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Fibroblast Growth Factor Receptor 1 (FGFR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Fibroblast Growth Factor Receptor 1 (FGFR1) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Fibroblast growth factor receptor 1 (FGFR1) FGFR1 is a transmembrane tyrosine kinase receptor that binds fibroblast growth factors (FGFs), playing a critical role in cellular proliferation, differentiation, and survival. FGFR1 consists of an extracellular ligand-binding domain composed of three immunoglobulin-like loops, a single transmembrane helix, and an intracellular tyrosine kinase domain. Upon FGF binding, FGFR1 undergoes dimerization and autophosphorylation, triggering downstream signaling pathways such as the MAPK, PI3K-AKT, and PLCγ pathways. FGFR1 is essential in embryonic development, angiogenesis, and tissue repair, and its dysregulation is implicated in various cancers, including lung and breast cancer, where aberrant FGFR1 activation promotes tumor growth and survival. FGFR1 is also involved in skeletal development, and mutations in the FGFR1 gene can lead to developmental disorders such as Pfeiffer syndrome. Its widespread expression in multiple tissues highlights its diverse biological roles.

Características del producto

category

ELISA Kits


immunogen target

Fibroblast Growth Factor Receptor 1 (FGFR1)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

H2,H3,H4,5,CEK,FLG,BFGFR,N-SAN,CD331,FGFR-1,Proto-oncogene c-Fgr,Fms-like tyrosine kinase 2,Pfeiffer syndrome


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

FGFR1


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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