Rat Fatty Aldehyde Dehydrogenase (ALDH3A2) ELISA Kit
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Description
Rat Fatty Aldehyde Dehydrogenase (ALDH3A2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Fatty aldehyde dehydrogenase concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Fatty Aldehyde Dehydrogenase (ALDH3A2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P30839 |
| Alias | ALDH3A2,ALDH10,FALDH |
| Background | Elisa kits for ALDH3A2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ALDH3A2, also known as fatty aldehyde dehydrogenase (FALDH), is a key enzyme that catalyzes the oxidation of fatty aldehydes to fatty acids. This process is essential for lipid metabolism, particularly in the breakdown of long-chain and very-long-chain fatty aldehydes derived from sphingolipids and dietary fats. Mutations in ALDH3A2 cause Sjögren-Larsson Syndrome (SLS), a rare autosomal recessive disorder characterized by ichthyosis (skin scaling), spasticity, and intellectual disability due to the accumulation of fatty aldehydes and disruption of lipid homeostasis. ALDH3A2 is expressed in the liver, brain, and skin, where it supports lipid metabolism and protects against oxidative stress. Its role in maintaining cellular membrane integrity and energy balance highlights its importance in metabolic and neuroprotective functions. Therapies targeting ALDH3A2 aim to restore fatty acid metabolism and alleviate symptoms of SLS, emphasizing its role in lipid-mediated pathologies.
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