Rat FAS/CD95(Factor Related Apoptosis) ELISA Kit

Product specifications

ELISA Kits

rat

Colorimetric

Quantitative

Sandwich ELISA, Double Antibody

31.25-2000pg/ml

96T

Serum,Plasma,Tissue homogenates,Other biological fluids

Shipped within 10-14 working days.

2-8 °C for 6 months

Q63199

APT1,CD95,FAS1,APO-1,FASTM,ALPS1A,TNFRSF6,Apo-1 antigen,Apoptosis-mediating surface antigen FAS,FASLG receptor

Elisa Kits FAS

RUO

Tumor necrosis factor receptor superfamily member 6 (FAS), also known as CD95, is a cell surface receptor involved in the regulation of apoptosis through the extrinsic pathway FAS belongs to the TNF receptor family and triggers apoptosis upon binding with its ligand, FASL This interaction activates the caspase cascade, leading to programmed cell death FAS-mediated apoptosis plays a critical role in immune system regulation, particularly in eliminating autoreactive T-cells during immune tolerance and in regulating the survival of activated immune cells In addition to immune regulation, FAS signaling is involved in tumor progression, where altered expression of FAS or its ligand can either promote or inhibit cancer cell survival In many cancers, FAS expression is dysregulated, contributing to resistance to apoptosis and enabling tumor cell evasion from immune surveillance FAS has also been implicated in autoimmune diseases, where inappropriate activation or inhibition of FAS signaling can lead to tissue damage and chronic inflammation

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