Rat Dopamine Receptor D5 (DRD5) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Dopamine Receptor D5 (DRD5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx511031
tested applications
ELISA
Description
Rat Dopamine Receptor D5 (DRD5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat D(1B) dopamine receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Dopamine Receptor D5 (DRD5) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P25115 |
| Alias | DRD5,DRD1B,DRD1L2,D(1B) dopamine receptor,dopamine receptor 5,Gpcr1,DBDR |
| Background | Elisa kits for DRD5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DRD5 is a G protein-coupled receptor of the D1-like dopamine receptor family that couples to Gs proteins, leading to activation of adenylate cyclase and an increase in cyclic AMP (cAMP) levels. DRD5 is highly expressed in limbic brain regions, including the hippocampus, hypothalamus, and cerebral cortex, where it modulates cognition, memory, and emotional behavior. DRD5 has a higher affinity for dopamine compared to DRD1, allowing it to regulate synaptic transmission and plasticity more effectively. It plays a key role in learning, working memory, and behavioral flexibility, with its dysfunction linked to schizophrenia, cognitive deficits, and neurological disorders. DRD5 is also involved in regulating motor function and reward pathways, contributing to the dopaminergic control of behavior. In peripheral tissues, DRD5 is expressed in renal, cardiovascular, and immune systems, where it regulates sodium balance, blood pressure, and immune cell activity. Dysregulation of DRD5 signaling has been associated with hypertension and autoimmune diseases. DRD5 is a potential therapeutic target for neuropsychiatric disorders, cognitive impairment, and cardiovascular dysfunction, given its role in dopamine-mediated signaling and cellular homeostasis.
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