Rat DMP1 (Dentin matrix acidic phosphoprotein 1) QuickTest ELISA Kit

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935106861
info@markelab.com
name
Rat DMP1 (Dentin matrix acidic phosphoprotein 1) QuickTest ELISA Kit
category
ELISA Kits
provider
FineTest
reference
QT-ER1951
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Rat
Assay Data
120 minutes
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P98193
Alias
Dentin matrix acidic phosphoprotein 1, DMP-1, Dentin matrix protein 1, DMP1
Background
Elisa kits for DMP1
Status
RUO

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DMP1 antibody

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.

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