Rat Cluster of Differentiation 3d (CD3D) Protein

Este producto es parte de CD3D - CD3 delta subunit of T-cell receptor complex
Rat Cluster of Differentiation 3d (CD3D) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein CD3D

proveedor

Abbexa

reference

abx065926

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Cluster Of Differentiation 3d (CD3d) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

CD3D, the delta subunit of the T-cell receptor (TCR) complex, plays a critical role in T-cell development and activation, which are essential components of the adaptive immune system. The TCR complex is responsible for recognizing antigens presented by major histocompatibility complex (MHC) molecules on the surface of antigen-presenting cells (APCs), allowing T-cells to initiate immune responses against pathogens. The CD3D subunit, along with other CD3 subunits (CD3E, CD3G, and CD3Z), functions as part of the CD3 complex, which couples with the TCR α/β heterodimer to mediate signal transduction following antigen recognition. The CD3D gene, located on chromosome 11q23, encodes the CD3δ chain, a 20-25 kDa protein essential for the assembly and function of the TCR complex. The CD3 complex, including the CD3D subunit, is expressed in all T lymphocytes and plays a vital role in transmitting signals from the extracellular environment to the interior of the cell, initiating downstream signaling cascades essential for T-cell activation, differentiation, and survival.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Cluster of Differentiation 3d (CD3D)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 10.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe22-Gly106 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD3D


dry ice

No


availability

Shipped within 5-12 working days.


alias

T3D,IMD19,CD3DELTA,CD3-DELTA,T-cell surface glycoprotein CD3 delta chain,T-cell receptor T3 delta chain


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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