Rat Cell Adhesion Molecule 4 (CADM4) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Cell Adhesion Molecule 4 (CADM4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx504632
tested applications
ELISA
Description
Rat Cell Adhesion Molecule 4 (CADM4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Cell adhesion molecule 4 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cell Adhesion Molecule 4 (CADM4) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q1WIM1 |
| Alias | NECL4,TSLL2,IGSF4C,Necl-4,synCAM4,TSLC1-like protein 2,Nectin-like protein 4,Immunoglobulin superfamily member 4C |
| Background | Elisa kits for CADM4 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CADM4, also known as SynCAM4 or nectin-like molecule 4 (Necl-4), is a member of the immunoglobulin superfamily and plays a critical role in cell-cell adhesion, particularly in epithelial and nervous tissues. It mediates both homophilic and heterophilic interactions, contributing to cellular polarity, tight junction formation, and signal transduction. CADM4 is expressed in a wide range of tissues, including the prostate, brain, and skin, where it is involved in maintaining epithelial integrity and regulating cell proliferation. Dysregulation of CADM4 is associated with tumorigenesis, as its downregulation has been observed in various cancers, including lung, prostate, and bladder cancers, suggesting its role as a tumor suppressor. It interacts with intracellular scaffolding proteins and cytoskeletal regulators, enabling its involvement in signaling pathways that influence cell migration and invasion. CADM4's extracellular domains mediate adhesion, while its intracellular domains anchor to cytoskeletal components, reinforcing its structural and signaling roles. Emerging research indicates that CADM4 may also influence immune responses and neuronal synaptic organization, highlighting its diverse functional significance.
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