Rat Calcitonin Gene Related Peptide 2 / CGRP2 (CALCB) Peptide
proveedor
Abbexareference
abx265668Tested Applications
reactivity
status
RUOclonality
Descripción
Calcitonin Gene Related Peptide II is a peptide.
Background
Calcitonin gene-related peptide, (CGRP) is a neuropeptide secreted and stored in the nervous system. In humans, CGRP exists in two forms: CGRP alpha (α-CGRP or CGRP I), a 37-amino acid neuropeptide produced through alternative splicing of the CALCA gene (CALC1) and CGRP beta (β-CGRP or CGRP II), which is encoded by a separate, nearby gene known as CALCB (CALC2). These two forms differ only by three amino acids.N-terminal disulfide bond and an amidated C-terminus and allows CGRP to bind to its receptorCGRP has a protective role in various cardiovascular diseases and its involvement in migraines has also been proven. Additionally, it has been discovered that CGRP serves as a crucial link between the nervous system and the skeletal muscle system. CGRP plays a multifaceted role by promoting osteogenesis, inhibiting bone resorption, facilitating vascular growth, and regulating the immune microenvironment.
Características del producto
category
Proteins and Peptides
origin
Rat
immunogen target
Calcitonin Gene Related Peptide 2 / CGRP2 (CALCB)
conjugation
Unconjugated
size 1
1 mg
size 2
2.5 mg
buffer
Not applicable.
storage
Store dry at -20 °C. Avoid repeated freeze/thaw cycles.
dry ice
No
availability
Shipped within 10-20 working days.
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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