Calcitonin Gene Related Peptide 1 / CGRP1 (CALCA) is a recombinant Rat protein produced in E. coli using Prokaryotic expression.
Calcitonin gene-related peptide, (CGRP) is a neuropeptide secreted and stored in the nervous system. In humans, CGRP exists in two forms: CGRP alpha (α-CGRP or CGRP I), a 37-amino acid neuropeptide produced through alternative splicing of the CALCA gene (CALC1) and CGRP beta (β-CGRP or CGRP II), which is encoded by a separate, nearby gene known as CALCB (CALC2). These two forms differ only by three amino acids.N-terminal disulfide bond and an amidated C-terminus and allows CGRP to bind to its receptorCGRP has a protective role in various cardiovascular diseases and its involvement in migraines has also been proven. Additionally, it has been discovered that CGRP serves as a crucial link between the nervous system and the skeletal muscle system. CGRP plays a multifaceted role by promoting osteogenesis, inhibiting bone resorption, facilitating vascular growth, and regulating the immune microenvironment.
Proteins and Peptides
Rat
E. coli
Calcitonin Gene Related Peptide 1 / CGRP1 (CALCA)
E. coli
Unconjugated
Lyophilized
WB, SDS-PAGE
10 µg
50 µg
100 µg
200 µg
1 mg
Recombinant
> 95%
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
CALCA
No
Shipped within 5-12 working days.
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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