Rat Cadherin 8 (CDH8) Protein
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Description
Rat Cadherin-8 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat CDH8 (NP_445845.2)(Met1-Met621) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Cadherin 8 |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: 65.9 kDa Sequence Fragment: Met1-Met621 Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 80% (SDS-PAGE) |
| Size 1 | 50 µg |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_445845.2 |
| Background | Protein CDH8 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Cadherin 8 (CDH8) Antibody
CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
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