Rat Bdnf/Nt-3 Growth Factors Receptor (NTRK2) Protein

Este producto es parte de NTRK - neurotrophic receptor tyrosine kinase
Product Graph
312€ (20 µg)

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935106861
info@markelab.com
name
Rat Bdnf/Nt-3 Growth Factors Receptor (NTRK2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694313
tested applications
SDS-PAGE

Description

Rat Bdnf/Nt-3 Growth Factors Receptor (NTRK2) Protein is a recombinant Rat protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Host
HEK293 cells
Origin
Rat
Observed MW
Molecular Weight: Calculated MW: 47.08 kDa  Observed MW (SDS-PAGE): 60 kDa
Sequence Fragment: Met1-His429
Tag: C-terminal His tag
Expression
Recombinant
Purity
>95% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Form
Lyophilized Reconstitute in sterile H2O. Do not vortex.
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.
Availability
Shipped within 5-15 working days.
Storage
Store lyophilized between -20 °C and -80 °C.
Dry Ice
No
UniProt ID
Q63604
Gene ID
2554
Alias
OBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor
Background
Protein NTRK2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.

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