Rat BAK1 (BCL2 Antagonist/Killer 1) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Rat BAK1 (BCL2 Antagonist/Killer 1) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
ER0760
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.781-50ng/ml |
| Sensitivity | 0.469ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q9JK59 |
| Alias | BAK,BAK-LIKE,BCL2L7,CDN1,Bcl-2 homologous antagonist/killer,Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7 |
| Background | Elisa kits for BAK1 |
| Status | RUO |
Background
BCL2 antagonist/killer 1 (BAK1) is a pro-apoptotic member of the Bcl-2 family of proteins, which regulate cell death pathways and cellular survival BAK1 plays a critical role in mitochondrial-mediated apoptosis, where it promotes the release of cytochrome c from the mitochondria, triggering the activation of caspase enzymes that lead to programmed cell death It functions as a key mediator of apoptosis in response to cellular stress, DNA damage, and oncogenic signaling, making it essential for maintaining cellular homeostasis and preventing the accumulation of damaged cells BAK1's activation is tightly regulated by anti-apoptotic proteins like Bcl-2, and its dysregulation is commonly associated with cancer, where loss of BAK1 function allows tumor cells to evade apoptosis, promoting tumor growth and resistance to chemotherapy Studies have also linked BAK1 to neurodegenerative diseases, where its dysregulation may contribute to neuronal loss and dysfunction Additionally, BAK1 has been implicated in immune responses, where it regulates T-cell homeostasis and immune cell survival, underscoring its broader role in cellular death and immune regulation
Productos relacionados
Bcl-2 Homologous Antagonist/Killer (BAK1) Antibody
BAK1 Antibody is a Rabbit Polyclonal antibody against BAK1. The protein encoded by this gene belongs to the BCL2 protein…
Ver producto
Bcl-2 Homologous Antagonist/Killer (BAK1) Antibody
Rabbit polyclonal antibody against Bak protein. Immunogen region is N-terminal.…
Ver producto
Bak (BH3 Domain Specific) Antibody
BAK belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti or pro-apopto…
Ver producto