Rat B-cell lymphoma/leukemia 10 (BCL10) ELISA Kit

Este producto es parte de BCL10 immune signaling adaptor
Rat B-cell lymphoma/leukemia 10 (BCL10) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for BCL10

proveedor

Abbexa

reference

abx256682

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat B-cell lymphoma/leukemia 10 (BCL10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat B-Cell Leukemia/Lymphoma 10 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

B-cell lymphoma/leukemia 10 (BCL10) is an essential signaling molecule involved in the regulation of immune cell activation, particularly in T-cell and B-cell responses BCL10 functions as a scaffolding protein in the activation of the NF-κB pathway, which is crucial for regulating inflammation, immune responses, and cell survival BCL10 forms a complex with other proteins, such as MALT1, to initiate signaling cascades that lead to immune cell activation and proliferation Its dysregulation has been linked to lymphoid malignancies, such as MALT lymphoma, where mutations or overexpression of BCL10 promote cancer cell proliferation and survival BCL10 is also involved in the regulation of apoptosis and cell differentiation, particularly in the context of immune cell maturation In addition to its role in immune cells, BCL10 has been shown to influence inflammatory diseases and autoimmunity, making it a potential target for therapeutic intervention

Características del producto

category

ELISA Kits


immunogen target

B-cell lymphoma/leukemia 10 (BCL10)


reactivity

Rat


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

18.8 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

CARMEN,CIPER,CLAP,IMD37,c-E10 Me10,CARD-containing molecule enhancing NF-kappa-B,CARD-like apoptotic protein, hCLAP


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

BCL10


dry ice

No


NCBI accession

NP_112618.1


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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