Rat B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) ELISA Kit

Este producto es parte de TNFRSF13C - TNF receptor superfamily member 13C
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585€ (96 tests)

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935106861
info@markelab.com
name
Rat B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx256728
tested applications
ELISA

Description

Rat B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C) concentrations in serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
B-Cell Activation Factor Receptor / BAFFR (TNFRSF13C)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
62.5 pg/ml - 4000 pg/ml
Sensitivity
37.5 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Tumor necrosis factor receptor superfamily member 13C,BAFFR,CD268,CVID4,BAFF-R,BROMIX,prolixin,B-cell-activating factor receptor,BAFF receptor,BAFF-R
Background
Elisa kits for TNFRSF13C
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

TNFRSF13C, also known as the B-cell activating factor receptor (BAFF-R), is a critical receptor involved in the regulation of B cell survival and maturation within the immune system. It belongs to the tumor necrosis factor receptor superfamily (TNFRSF), with BAFF-R specifically binding BAFF (B-cell activating factor), also known as TNFSF13B. BAFF-R signaling is essential for the differentiation of B cells and their progression through developmental stages, playing a crucial role in both innate and adaptive immunity. Dysfunction in TNFRSF13C signaling has been implicated in immune-related disorders, including autoimmune diseases and immunodeficiencies. Genetic mutations or dysregulation in BAFF-R and BAFF signaling pathways are associated with conditions such as Systemic Lupus Erythematosus (SLE) and Common Variable Immunodeficiency (CVID), as they can lead to abnormal B cell activity, autoreactivity, and altered antibody production. This receptor is also studied as a therapeutic target for autoimmune diseases, with strategies aimed at modulating BAFF levels to control B cell activity.

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