Rat ATP Binding Cassette Subfamily G Member 8 (ABCG8) Protein

Este producto es parte de ABCG - ATP Binding Cassette Subfamily G
Rat ATP Binding Cassette Subfamily G Member 8 (ABCG8) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ABCG8

proveedor

Abbexa

reference

abx650408

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat ABCG8 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

ABCG8 is a membrane-bound transporter belonging to the ABCG subfamily and works as a heterodimer with ABCG5. Expressed mainly in the liver and intestine, it plays a critical role in regulating sterol transport, particularly in the excretion of cholesterol and plant sterols into bile. ABCG8 helps maintain sterol homeostasis and prevent excess sterol absorption. Mutations in ABCG8 are associated with sitosterolemia, leading to sterol accumulation and increased cardiovascular risk. This transporter is crucial for lipid metabolism and overall sterol balance.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

ATP Binding Cassette Subfamily G Member 8 (ABCG8)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 34.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Gln271 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ABCG8


dry ice

No


availability

Shipped within 5-7 working days.


alias

GBD4,STSL,STSL1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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