Rat Aryl Hydrocarbon Receptor (AHR) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for AHR
proveedor
Abbexareference
abx572480Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Aryl Hydrocarbon Receptor (AHR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aryl Hydrocarbon Receptor (AHR) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AHR is a ligand-activated transcription factor involved in sensing and responding to environmental toxins, such as dioxins and polycyclic aromatic hydrocarbons (PAHs). Upon ligand binding, AHR translocates from the cytoplasm to the nucleus, where it forms a heterodimer with the Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) and binds to DNA at xenobiotic response elements (XREs), regulating the expression of detoxification enzymes like CYP1A1 and CYP1B1. AHR is expressed in a variety of tissues, including the liver, skin, and immune system, and plays roles in xenobiotic metabolism, immune regulation, cell differentiation, and circadian rhythm modulation. Dysregulation of AHR activity is implicated in immune dysfunction, autoimmune diseases, and cancer, where it influences tumor progression and metastasis. AHR’s dual role in both normal homeostasis and pathological conditions makes it a target of interest in toxicology, immunology, and cancer research.
Características del producto
category
ELISA Kits
immunogen target
Aryl Hydrocarbon Receptor (AHR)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.09 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
RP85,bHLHe76
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AHR
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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