Rat Arginine Vasopressin Receptor 1A (AVPR1A) CLIA Kit
643.5€ (96 tests)
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name
Rat Arginine Vasopressin Receptor 1A (AVPR1A) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196728
tested applications
CLIA
Description
Rat Arginine Vasopressin Receptor 1A (AVPR1A) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Arginine Vasopressin Receptor 1A (AVPR1A).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Arginine Vasopressin Receptor 1A (AVPR1A) |
| Reactivity | Rat |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 93.75 ng/ml - 6000 ng/ml |
| Sensitivity | 56.25 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AVPR1A,V1aR,AVPR1,antidiuretic hormone receptor 1a,AVPRAVPR V1a |
| Background | CLIA Kits AVPR1A |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AVPR1A is a G protein-coupled receptor that is activated by arginine vasopressin (AVP), a hormone involved in regulating water balance, blood pressure, and social behaviors. AVPR1A primarily couples to Gq proteins, leading to the activation of phospholipase C (PLC) and the increase of intracellular calcium, which results in smooth muscle contraction and vasoconstriction. It is predominantly expressed in the smooth muscle cells of blood vessels, kidneys, and the central nervous system. AVPR1A’s role in regulating water retention by the kidneys and controlling blood vessel constriction makes it a key player in maintaining blood pressure and fluid balance. In the brain, AVPR1A is involved in modulating social behaviors, such as bonding and aggression. Dysregulation of AVPR1A is associated with cardiovascular diseases like hypertension, as well as psychiatric conditions such as autism and social anxiety. AVPR1A antagonists are being developed as potential treatments for hypertension, heart failure, and social behavior disorders.
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