Rat Apolipoprotein D (APOD) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein APOD
proveedor
Abbexareference
abx065424Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Apolipoprotein D (APOD) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
Apolipoprotein D (APOD) is a unique member of the apolipoprotein family, functioning as a lipid transporter in the plasma and extracellular fluids. Unlike other apolipoproteins, APOD is not synthesized in the liver but is predominantly produced in the central nervous system (CNS), liver, kidneys, and mammary glands. APOD associates with high-density lipoprotein (HDL) and contributes to cholesterol transport, as well as lipid metabolism. Structurally, APOD is classified as a member of the lipocalin family, which binds small hydrophobic molecules, such as arachidonic acid and cholesterol. It has a prominent role in antioxidant defense by neutralizing reactive oxygen species (ROS) and reducing oxidative stress, particularly in the CNS. APOD is upregulated during injury and neurodegenerative conditions, including Alzheimer’s disease, Parkinson’s disease, and stroke, indicating its neuroprotective function. Elevated levels of APOD are also found in cancer, cardiovascular disease, and diabetes, suggesting its role in cellular stress responses. APOD may regulate inflammation, cellular lipid homeostasis, and signal transduction, making it a promising biomarker and therapeutic target in age-related disorders, metabolic syndromes, and neurological diseases.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Apolipoprotein D (APOD)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 21.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln21-Leu189 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
APOD
dry ice
No
availability
Shipped within 5-12 working days.
alias
APOD, Apod, apolipoprotein D
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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