Rat Angiopoietin-Related Protein 4 (ANGPTL4) Protein

Este producto es parte de ANGPTL - Angiopoietin Like
Product Graph
195€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Rat Angiopoietin-Related Protein 4 (ANGPTL4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065338
tested applications
WB, SDS-PAGE

Description

Rat ANGPTL4 is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Angiopoietin-Related Protein 4 (ANGPTL4)
Host
E. coli
Origin
Rat
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 30.8 kDa  Observed MW (SDS-PAGE): 34 kDa  Possible reasons why the actual band size differs from the predicted band size: 1. Splice variants. Alternative splicing may create different sized proteins from the same gene. 2. Relative charge. The composition of amino acids may affect the charge of the protein. 3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size. 4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form. 5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed.

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Arg182-Leu394

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q6TMA8
Alias
ARP4,FIAF,HARP,HFARP,NL2
Background
Protein ANGPTL4
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ANGPTL4 is a secreted glycoprotein that plays key roles in lipid metabolism, angiogenesis, and inflammation. ANGPTL4 functions as an inhibitor of lipoprotein lipase (LPL), regulating triglyceride hydrolysis and fatty acid release, particularly during fasting and energy deprivation. It is expressed in adipose tissue, liver, and muscle, where it coordinates energy balance and lipid transport. ANGPTL4 also modulates angiogenesis by inhibiting endothelial cell proliferation and migration, making it a negative regulator of vascular growth. In cancer, ANGPTL4 has context-dependent roles, promoting metastasis by enhancing tumor cell migration and vascular permeability while inhibiting angiogenesis in certain conditions. Elevated ANGPTL4 levels are associated with obesity, diabetes, and atherosclerosis, where it contributes to dyslipidemia and chronic inflammation. Its ability to regulate lipid metabolism, angiogenesis, and inflammation makes ANGPTL4 a potential target for treating metabolic disorders, cardiovascular disease, and cancer.

Related Products

EH0038

Human ANGPTL4 (Angiopoietin-related protein 4) ELISA Kit

Ver Producto
EM0721

Mouse ANGPTL4 (Angiopoietin Like Protein 4) ELISA Kit

Ver Producto
ER2104

Rat ANGPTL4 (Angiopoietin-related protein 4) ELISA Kit

Ver Producto