Rat Angiopoietin-Related Protein 4 (ANGPTL4) CLIA Kit

Este producto es parte de ANGPTL - Angiopoietin Like
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845€ (96 tests)

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935106861
info@markelab.com
name
Rat Angiopoietin-Related Protein 4 (ANGPTL4) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx492329
tested applications
CLIA

Description

Rat Angiopoietin Like Protein 4 (ANGPTL4) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Angiopoietin-Related Protein 4 (ANGPTL4)
Reactivity
Rat
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
1.56 ng/ml - 100 ng/ml
Sensitivity
< 0.59 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
ARP4,FIAF,HARP,HFARP,NL2
Background
CLIA Kits ANGPTL4
Status
RUO
Note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ANGPTL4 is a secreted glycoprotein that plays key roles in lipid metabolism, angiogenesis, and inflammation. ANGPTL4 functions as an inhibitor of lipoprotein lipase (LPL), regulating triglyceride hydrolysis and fatty acid release, particularly during fasting and energy deprivation. It is expressed in adipose tissue, liver, and muscle, where it coordinates energy balance and lipid transport. ANGPTL4 also modulates angiogenesis by inhibiting endothelial cell proliferation and migration, making it a negative regulator of vascular growth. In cancer, ANGPTL4 has context-dependent roles, promoting metastasis by enhancing tumor cell migration and vascular permeability while inhibiting angiogenesis in certain conditions. Elevated ANGPTL4 levels are associated with obesity, diabetes, and atherosclerosis, where it contributes to dyslipidemia and chronic inflammation. Its ability to regulate lipid metabolism, angiogenesis, and inflammation makes ANGPTL4 a potential target for treating metabolic disorders, cardiovascular disease, and cancer.

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